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| Dr. R. Scot Payne, Assistant Professor of Biology |
| Dr. Scot Payne, Assistant Professor of Biology
rspayne@kwc.edu
(270) 852-3185
Yu Hak Hahn #101 | Education
B.S., Biology, Brescia College, 1983
M.S., Comparative Physiology, University of Kentucky, 1987
Ph.D., Pharmacology/Toxicology, University of Louisville, 2001 Course Subjects
Anatomy & Physiology
Comparative Physiology
Neuroscience
Pharmacology
Human Ecology
Biology (non-majors) Research Interests
Neuroprotection
Neuropharmacology
Learning Paradigms
Neurobiology of Music Research Funding
- Co-Investigator. Inogene (France) Kalsolac infusion: Neuroprotection from traumatic brain injury. (2006).
- Co-Principal Investigator. Forest Labs (USA) Neuroprotection in an animal model of bipolar disorder. (2007).
Recent Presentations
- R.S. Payne and A. Schurr: The stress hormone corticosterone inhibits glucose-, but not lactate-supported hippocampal LTP. J Cereb Blood Flow Metab 25: S67-S67, (2005).
Rif El-Mallakh, Joshua Lord, Ralphiel S. Payne, Avital Schurr, Pradeep Banerjee: Memantine inhibits ouabain-evoked “cycling” in rat hippocampal slices. Society for Biological Psychiatry April (2007).
- R. Scot Payne, PhD, Heather Tluczek,MD, Avital Schurr, PhD, Ozan Akça, MD. Predictors Of Survival After Cardiac Arrest Under General Anesthesia. ASA October (2007).
- Hisham Taher; Yiru Guo; Ralphiel S Payne; Greg Hunt; Robert J Vincent; Santosh K SanganalMath; Nathan J Reed; Ewa K Zuba-Surma; Smita Ranjan; Sumit Tiwari; Arash Rezazadeh; Rif S El-Mallakh; Roberto Bolli; Buddhadeb Dawn. Pharmacologic Late Preconditioning with Opioid 1-agonist Confers Cardio- and Neuroprotective Benefits During Cardiac Arrest. Circulation, 116:11-21, 2007 Recent Peer-Reviewed Publications
- Payne, R.S., Goldbart, A., Gozal, D., and Schurr, A. Effect of intermittent hypoxia on long-term potentiation in rat hippocampal slices. Brain Res. 1029(2), 195-199, 2004.
- Payne, R.S., Akca, O., Roewer, N., Schurr, A., and Kehl, F. Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats. Brain Res. 1034, 147-152, 2005.
- Schurr, A. and Payne, R.S. Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. Neuroscience Jul 13;147(3):613-9. 2007.
- Payne, R.S. and Schurr, A. Corticosterone disrupts glucose-, but not lactate-supported hippocampal PS-LTP. Neurosci. Lett. Sep 7;424(2):111-5, 2007. Book Chapters
- Schurr, A., Payne, R. S., and Rigor, B. M. Diltiazem and MK-801 but not APV act synergistically to protect rat hippocampal slices against hypoxic damage. In: Neurodegenerative diseases ’95: Molecular and Cellular Mechanisms and Therapeutic Advances. G. Fiskum, Ed. Plenum Press, New York, (1995).
- Schurr, A., Payne, R. S., Levy, R. S., and Rigor, B. M. Understanding cerebral energy metabolism: A key to successful neuroprotection, In: Baillier’s Clinical Anesthesiology: Neuroprotection. J. A. Stamford and L. Strunin, Eds. Baillier Tindal, London, pp. 409-425, (1996).
- Schurr, A., Payne, R. S., Miller, J. J., and Rigor, B. M. Direct evidence that lactate is an obligatory aerobic energy substrate for functional recovery posthypoxia in vitro. In: Progress in Alzheimer’s and Parkinson’s Diseases. A. Fisher, M. Yoshida, and I. Hanin, Eds, Plenum, New York (1999).
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